,
 
Edorium Journal of

Infectious Diseases

 
  Table of Contents    
Original Article
 
Characterization of essential oil from the seed of Eucalyptus cloeziana and evaluation of its modes of medicinal potentials
Ololade ZS1,2, Olawore NO2
1Department of Chemical and Food Sciences, Bells University of Technology, Ota, Nigeria
2Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria

Article ID: 100005I03ZO2017
doi:10.5348/I03-2017-5-OA-4

Address correspondence to:
Zacchaeus S. OLOLADE
Department of Chemical and Food Sciences
Bells University of Technology
Ota, Ogun State
Nigeria-112212

Access full text article on other devices

  Access PDF of article on other devices

[HTML FULL TEXT]   [PDF Full Text] [Print This Article]
[Similar article in Pumed] [Similar article in Google Scholar]

How to cite this article
Ololade ZS, Olawore NO. Characterization of essential oil from the seed of Eucalyptus cloeziana and evaluation of its modes of medicinal potentials. Edorium J Infect Dis 2017;3:1–8.


Abstract
Aims: Different parts of Eucalyptus plants are widely used in medicine for the prevention and treatment of diseases. This study examined the phytochemicals and medicinal properties of the seed essential oil of E. cloeziana from Nigeria.
Methods: The essential oil was extracted by hydrodistillation and analyzed using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). TPC, antioxidant, anti-inflammatory, antinociceptive and antimicrobial activities were measured by Folin-Ciocalteu’s, DPPH, FRAP, carrageenan, formalin and agar-well diffusion methods respectively.
Results: The GC and GC-MS analyses revealed the presence of 33 phytochemicals making up 99.7% of the total percentage composition of the essential oil. The most abundant component was 1, 8-cineole (23.8%). The TPC was 199.18±0.0 µgmg-1 gallic acid equivalents. The antioxidant IC50 value of the essential oil was 2.8 µgml-1 and it was capable of scavenging free radicals in a range of 62.6–70.3%, the seed essential showed strong antioxidant activity with AAI higher than that of ascorbic acid. The reduction antioxidant potential of the essential oil was EC50: 1.5 µgml-1. The essential oil gave high anti-inflammatory with value of 68.8% and antinociceptive properties by inhibition in both neurogenic (81.3%) and inflammatory pain (80.3%). The essential oil was active against all the tested bacteria with high zones of inhibition (8.0–20.0 mm).
Conclusion: Therefore, the seed essential oil of E.cloeziana is a sustainable and promising source of natural product with good therapeutic properties.

Keywords: Eucalyptus cloeziana, Medicinal properties, Phytochemicals, Seed essential oil


[HTML FULL TEXT]   [PDF Full Text]

Author Contributions
Ololade Z.S. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Olawore N.O. – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2017 Z.S Ololade et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



  Home line About the Journal line Aim and Scope line Open Access line Archives
Apply as Editor line Apply as Reviewer line Submit Reviews - Editors line Submit Reviews - Reviewers
Instructions for Authors line Templates to Use line Copyright Form line Author Checklist
Online Submission line Email Submission line Submit Revision line Submit All Forms line Submit Page Proofs
Terms of Service line Privacy policy line Disclaimer line FAQ line Contact: Journal line Contact: Edorium Journals line Site Map
 
  Copyright © 2017. Edorium. All rights reserved.